Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
نویسندگان
چکیده
We evaluated the results of limb-sparing surgery and reconstruction of bone defects with vascularized fibula grafts in 8 consecutive patients (mean age at operation 13.6 years (range 4.1-24.2 years), female/male = 6/2) with bone sarcomas (BS) (osteosarcoma/Ewing's sarcoma/chondrosarcoma= 4/3/1) operated on form 2000 to 2006. The bone defects reconstructed were proximal femoral diaphysis and epiphysis (n = 2), humeral diaphysis (n = 2), humeral proximal diaphysis and epiphysis (n = 1), femoral diaphysis (n = 1), ulnar diaphysis (n = 1), and tibial diaphysis (n = 1). One patient with Ewing's sarcoma had an early hip disarticulation, developed multiple metastases, and died 9 months after the operation. The remaining patients (n = 7) are all alive 50 months (range 26-75 months) after surgery. During the follow-up the following major complications were seen: 1-2 fractures (n = 4), pseudarthrosis (n = 2), and hip dislocation (n = 1). Limb-sparing surgery with reconstruction of bone defects using vascularized fibular grafts in BS cases is feasible with acceptable clinical results, but fractures should be expected in many patients.
منابع مشابه
Reconstructionof Human Mandibular Continuity Defects with Allogenic Scaffold and Autologousmarrow Mesenchymal Stem Cells
Background Mandibular continuity defects occur after tumor resection, maxillofacial injury, or osteomyelitis. Despite the current availability of a plethora of treatment modalities, bone substitutes, and various clinical adjuncts, an exact reconstructive recapitulation of large bony defects continues to be beyond reach. In this clinical pilot study, we report a novel method for reconstruction ...
متن کاملVascularised fibula graft for tumours
The reconstruction of long bone defects after tumor resection has been a challenge to the reconstructive surgeon. Increased survival of patients with aggressive or malignant tumors of the extremities has made microsurgical reconstruction more relevant in improving their quality of life. In order to avoid amputation, these long defects are often reconstructed with vascularized autogenous fibular...
متن کاملMandibular Reconstruction Using the Free Vascularized Fibula Graft: An Overview of Different Modifications
The reconstruction of the mandible is a complex procedure because various cosmetic as well as functional challenges must be addressed, including mastication and oral competence. Many surgical techniques have been described to address these challenges, including non-vascularized bone grafts, vascularized bone grafts, and approaches related to tissue engineering. This review summarizes different ...
متن کاملNon-vascularised fibula grafts for reconstruction of segmental and hemicortical bone defects following meta- /diaphyseal tumour resection at the extremities
BACKGROUND The reconstruction of meta-/diaphyseal bone defects following bone tumour resection is challenging, and biological treatment options should be applied whenever possible, especially in benign lesions and early stage sarcomas. We aimed to evaluate the results of segmental (SR) and hemicortical reconstructions (HR) at the extremities using non-vascularised fibula grafts. METHODS We re...
متن کاملReconstruction of mandibular defects with autogenous bone and decellularized bovine bone grafts with freeze-dried bone marrow stem cell paracrine factors
The gold standard following segmental mandibulectomy is vascularized autologous bone graft in the form of the fibula flap. However, in bone reconstruction the use of autogenous bone does not always guarantee a successful outcome. The aim of the present investigation was to develop a novel biologically active bone (BAB) graft, and to use it for the reconstruction of large size defects of the man...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2010 شماره
صفحات -
تاریخ انتشار 2010